| Catalog No. | Size | Price (USD) |
| 10560-R003-1 | 1 mL | $1,969.87 |
| 10560-R003-20 | 20 µL | $118.49 |
| 10560-R003-50 | 50 µL | $177.58 |
| 10560-R003-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-DOPA Decarboxylase/DDC Antibody, Rabbit Monoclonal |
| Validated applications | ELISA(Cap) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human DOPA Decarboxylase/DDC |
| Immunogen | Recombinant Human DOPA Decarboxylase / DDC Protein (Catalog#10560-H08B) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human DOPA Decarboxylase / DDC (rh DOPA Decarboxylase / DDC; Catalog#10560-H08B; NP_000781.1; Met1-Glu480). |
| Source | Monoclonal Rabbit IgG Clone #003 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AADC Antibody
Background Information
| Full Name | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| Description | Dopa Decarboxylase (DDC), also known as AADC and Aromatic-L-amino acid decarboxylase, is a 54 kDa member of the group II decarboxylase family of proteins.It is a vitamin B6-dependent homodimeric enzyme that catalyzes the decarboxylation of both L-3,4-dihydroxyphenylalanine (L-DOPA) and L-5-hydroxytryptophan to dopamine and serotonin, respectively, which are major mammalian neurotransmitters and hormones belonging to catecholamines and indoleamines. Since L-DOPA is regularly used to treat the symptoms of Parkinson's disease, the catalytic pathway is of particular research interest. Defects of DDC are associated with severe developmental delay, oculogyric crises (OGC), as well as autosomal recessive disorder AADC deficiency, an early onset inborn error in neurotransmitter metabolism which can lead to catecholamine and serotonin deficiency. |
| Research Areas |
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| References |
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title: Recombinant AAV vectors for treating neurodegenerative disorders
authors: Yezheng Tao; Shin-Shay Tian; Xiaoping Zhao
date: 2026-04-21
cited_by_count: 0
techniques: Blocking Assay; Construct; Control; Expressing; Transfection
bioz_score: 94
