| Catalog No. | Size | Price (USD) |
| 101147-T32-50 | 50 µL | $147.96 |
| 101147-T32-100 | 100 µL | $251.64 |
| 101147-T32-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Desmoglein 1/DSG1 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Desmoglein 1/DSG1 |
| Immunogen | A synthetic peptide corresponding to the center region of the Human DSG1 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human DSG1, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CDHF4 Antibody; Anti-DG1 Antibody; Anti-DSG Antibody; Anti-EPKHE Antibody; Anti-EPKHIA Antibody; Anti-PPKS1 Antibody; Anti-SPPK1 Antibody
Image / Experimental Information
| Image 1 Description | Anti-DSG1 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: K562 Whole Cell Lysate Lane C: 293 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size:114 kDa Observed band size:114 kDa (We are unsure as to the identity of these extra bands.) |
| Image 1 Alt Text | Human DSG1/Desmoglein 1 Western blot (WB) 6880 |
| Image 1 URL | Source image |
Background Information
| Full Name | desmoglein 1 |
| Description | Fogo selvagem (FS), the endemic form of pemphigus foliaceus (PF), is characterized by pathogenic anti-desmoglein 1 (DSG1) autoantibodies. The anti-DSG1 response in FS is antigen driven and that selection for mutant anti-DSG1 B cells begins well before the onset of disease. Dsg1, the prototype of the desmoglein family, is a major component of epidermal desmosomes and the antigenic target of antibodies found in the sera of patients with the blistering disease, pemphigus foliaceus. |
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