| Catalog No. | Size | Price (USD) |
| 10748-RP04-50 | 50 µL | $147.96 |
| 10748-RP04-100 | 100 µL | $251.64 |
| 10748-RP04-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-DPP2 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human DPP2 |
| Immunogen | Recombinant Human DPPII protein (Catalog#10748-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human DPPII (rhDPPII; Catalog#10748-H08H; NP_037511.2, Met 1-Leu 492). DPPII specific IgG was purified by human DPPII affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-DPP2 Antibody; Anti-DPPII Antibody; Anti-QPP Antibody
Background Information
| Full Name | dipeptidyl-peptidase 7 |
| Description | DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. It localizes to lysosomes. DPP7 localizes to lysosomes and exists as a homodimer via its leucine zipper motif and is involved in the degradation of oligopeptides. In response to calcium release, it can be secreted in its active form. It is essential for lymphocyte survival, as the inhibition of DPP7 results in quiescent cell apoptosis. |
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