| Catalog No. | Size | Price (USD) |
| 13911-R101-50 | 50 µL | $177.58 |
| 13911-R101-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-DYDC2 Antibody, Rabbit Monoclonal |
| Validated applications | ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human DYDC2 |
| Immunogen | Recombinant Human DPY30 domain containing 2 / DYDC2 Protein (Catalog#13911-H09E) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human DPY30 domain containing 2 / DYDC2 (rh DPY30 domain containing 2 / DYDC2; Catalog#13911-H09E; Q96IM9; Thr102-Pro176). |
| Source | Monoclonal Rabbit IgG Clone #101 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-bA36D19.6 Antibody; Anti-MGC16186 Antibody
Image / Experimental Information
| Image 1 Description | Immunofluorescence staining of Human DYDC2 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human DYDC2 monoclonal antibody (1:60) at 4℃ overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to nucleus. |
| Image 1 Alt Text | Human DPY30 domain containing 2 Immunofluorescence(IF) 2944 |
| Image 1 URL | Source image |
Background Information
| Full Name | DPY30 domain containing 2 |
| Description | DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. As part of the MLL1/MLL complex, DPY30 domain containing 2 is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 domain containing 2 may also play an indirect or direct role in endosomal transport. |
| References |
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