Anti-EBAG9 Antibody, Rabbit Polyclonal sinobiological 14012-RP01

$143.00
In stock
SKU
14012-RP01
Catalog No.SizePrice (USD)
14012-RP01-100100 µL$147.96
14012-RP01-200200 µL$251.64
14012-RP01-400400 µL$355.32

General Information

Product nameAnti-EBAG9 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman EBAG9
ImmunogenRecombinant Human RCAS1 / EBAG9 protein (Catalog#14012-H07E)
PreparationProduced in rabbits immunized with purified, recombinant Human RCAS1 / EBAG9 (rh EBAG9; Catalog#14012-H07E; O00559; Arg28-Ser213). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-EB9 Antibody; Anti-PDAF Antibody; Anti-RCAS1 Antibody

Background Information

Full Nameestrogen receptor binding site associated, antigen, 9
DescriptionRCAS1, also known as EBAG9, is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. RCAS1 gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor which binds to the estrogen-responsive element (ERE) found in the 5'-flanking region of RCAS1 gene. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for RCAS1 gene. EBAG9 may participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
References
  1. Ohshima K. et al., 2001, Clin Exp Immunol. 123 (3): 481-6.
  2. Ikeda K. et al., 2000, Biochem Biophys Res Commun. 273 (2): 654-60.
  3. Nakashima M. et al., 1999, Nat Med. 5 (8): 938-42.

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