Anti-ENPP-5 Antibody, Rabbit Polyclonal sinobiological 11519-RP01

$143.00
In stock
SKU
11519-RP01
Catalog No.SizePrice (USD)
11519-RP01-100100 µL$147.96
11519-RP01-200200 µL$251.64
11519-RP01-400400 µL$355.32

General Information

Product nameAnti-ENPP-5 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman ENPP-5
ImmunogenRecombinant Human ENPP5 protein (Catalog#11519-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human ENPP5 (rh ENPP5; Catalog#11519-H08H; Q9UJA9; Met1-Gly429). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-NPP-5 Antibody; Anti-NPP5 Antibody; Anti-UNQ550/PRO1107 Antibody

Background Information

Full Nameectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
DescriptionENPP5 is a member of the nucleotide pyrophosphatase/phosphodiesterase family (NPP). It is a family comprised of dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. There are seven isoforms in NPP family, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. NPP also belongs to the alkaline phosphatase (AP) superfamily of enzymes and they are located in the cell membrane and hydrolyze extracellular phosphate diesters to affect a wide variety of biological processes. ENPP5 belongs to a group of nucleotidemetabolizing ectoenzymes, which regulate the availability of extracellular nucleotides. ENPP5 may play a role in neuronal cell communication. However, it lacks nucleotide pyrophosphatase and lysopholipase D activity. It may also be involved in neuronal cell communication. The amino acid sequence of human ENPP5 is 100%, 88%, and 82% identical to that of chimpanzee, dog and mouse/rat. ENPP5 functions in phospholipid metabolism.
Research Areas
  • Phosphatases and Regulators
References
  1. Strausberg RL, et al. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
  2. Gerhard DS, et al. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14(10B):2121-7.
  3. Lamesch P, et al. (2007) hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics. 89(3):307-15.

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