| Catalog No. | Size | Price (USD) |
| 10235-MM04-50 | 50 µL | $147.96 |
| 10235-MM04-100 | 100 µL | $251.64 |
| 10235-MM04-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-EphB4 Antibody, Mouse Monoclonal |
| Validated applications | ELISA (FAQ Protocol), FCM (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human EphB4 |
| Immunogen | Recombinant Human EphB4 protein (Catalog#10235-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EphB4 / HTK extracellular domain (rhEphB4; Catalog#10235-H08H; NP_004435.3; Met 1-Ala 539). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #04 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CMAVM2 Antibody; Anti-EPHB4 Antibody; Anti-HFASD Antibody; Anti-HTK Antibody; Anti-LMPHM7 Antibody; Anti-MYK1 Antibody; Anti-TYRO11 Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of human EphB4 expression on MCF-7 cells. Cells were stained with purified anti-Human EphB4, then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells. |
| Image 1 Alt Text | Human EphB4/Eph Receptor B4 Flow Cytometry (FC) 5182 |
| Image 1 URL | Source image |
| Image 2 Description | Flow cytometric analysis of human EphB4 expression on MCF-7 cells. Cells were stained with purified anti-Human EphB4, then a FITC-conjugated second step antibody. The histogram were derived from events with the forward and side light-scatter characteristics of intact cells. |
| Image 2 Alt Text | Human EphB4/Eph Receptor B4 Immunofluorescence(IF) 14804 |
| Image 2 URL | Source image |
Background Information
| Full Name | EPH receptor B4 |
| Description | Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers. |
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