| Catalog No. | Size | Price (USD) |
| 10235-R001-A-25 | 25 Tests | $162.92 |
| 10235-R001-A-100 | 100 Tests | $325.84 |
General Information
| Product name | Recombinant Anti-EphB4 Antibody (APC), Rabbit Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human EphB4 |
| Immunogen | Recombinant Human EphB4 protein (Catalog#10235-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human EphB4 (rh EphB4; Catalog#10235-H08H; NP_004435.3; Met 1-Ala 539) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Source | Monoclonal Rabbit IgG Clone #001 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Concentration | 10 μl/Test, 0.1 mg/ml |
| Conjugate | APC |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! |
Synonyms: Anti-CMAVM2 Antibody; Anti-EPHB4 Antibody; Anti-HFASD Antibody; Anti-HTK Antibody; Anti-LMPHM7 Antibody; Anti-MYK1 Antibody; Anti-TYRO11 Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of anti-human EphB4 on MCF-7 cells. MCF-7 cells were detached using 1X trypsin, washed, then stained with APC Rabbit anti-human EphB4. |
| Image 1 Alt Text | Human EphB4 Flow Cytometry (FC) 26142 |
| Image 1 URL | Source image |
Background Information
| Full Name | EPH receptor B4 |
| Description | Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers. |
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