| Catalog No. | Size | Price (USD) |
| 12109-R001-20 | 20 µL | $118.49 |
| 12109-R001-50 | 50 µL | $177.58 |
| 12109-R001-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-FABP4/A-FABP Antibody, Rabbit Monoclonal |
| Validated applications | IHC-P (FAQ Protocol), FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human FABP4/A-FABP Has cross-reactivity in ELISA with Mouse FABP3 No cross-reactivity in ELISA with Human FABP6 |
| Immunogen | Recombinant Human FABP4 / ALBP / A-FABP protein (Catalog#12109-H07E) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human FABP4 / ALBP / A-FABP (rh FABP4 / ALBP / A-FABP; Catalog#12109-H07E; P15090; Cys2-Ala132,29Ala/Thr). |
| Source | Monoclonal Rabbit IgG Clone #001 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-A-FABP Antibody; Anti-AFABP Antibody; Anti-ALBP Antibody; Anti-aP2 Antibody; Anti-HEL-S-104 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human FABP4 in human lung cancer with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Human FABP4 /A-FABP Immunohistochemistry(IHC) 4211 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human FABP4 in human lung cancer with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 2 Alt Text | Human FABP4 /A-FABP Immunohistochemistry(IHC) 4212 |
| Image 2 URL | Source image |
| Image 3 Description | Immunochemical staining of human FABP4 in human lung cancer with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 3 Alt Text | Human FABP4 Flow Cytometry (FC) 20372 |
| Image 3 URL | Source image |
Background Information
| Full Name | fatty acid binding protein 4, adipocyte |
| Description | Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients. |
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