Recombinant Human FABP6 / ILBP / I-BABP protein (Catalog#12579-HNAE)
Preparation
Produced in rabbits immunized with purified, recombinant Human FABP6 / ILBP / I-BABP (rh FABP6 / ILBP / I-BABP; Catalog#12579-HNAE; AAH22489.1; Met 1-Ala 128). FABP6 / ILBP / I-BABP specific IgG was purified by Human FABP6 / ILBP / I-BABP affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. Isoform2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform1of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform2is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. FABP6 / I-BABP is a cancer-related protein that acts as an intracellular transporter of bile acid in the ileal epithelium. FABP6 / I-BABP may also play an important role in early carcinogenesis.
References
Kurz M., et al., 2003, Proteins 50:312-328.
Ohmachi,T. et al., 2006, Clin Cancer Res.12 (17):5090-5.
Fang C., et al., 2007, Cancer Res. 67:9039-9046.
Szczerbal,I. et al., 2007, Cytogenet Genome Res.118 (1):63-6.