| Catalog No. | Size | Price (USD) |
| 201156-T32-50 | 50 µL | $147.96 |
| 201156-T32-100 | 100 µL | $251.64 |
| 201156-T32-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-BLMH Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human BLMH |
| Immunogen | E. coli-derived Human BLMH fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human BLMH fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-BH Antibody; Anti-BMH Antibody
Image / Experimental Information
| Image 1 Description | Anti-BLMH rabbit polyclonal antibody at 1:500 dilution Lane A: HL-60 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:53 kDa Observed band size:53 kDa |
| Image 1 Alt Text | Human BLMH Western blot (WB) 28788 |
| Image 1 URL | Source image |
Background Information
| Full Name | bleomycin hydrolase |
| Description | The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The papain superfamily member bleomycin hydrolase (BLMH) is a neutral cysteine protease with structural similarity to a 20S proteasome. Bleomycin (BLM), a clinically used glycopeptide anticancer agent. BLMH is an essential protectant against BLM-induced death and has an important role in neonatal survival and in maintaining epidermal integrity. Sequencing revealed several putative sites phosphorylated by different types of protein kinases, but no signal sequence, transmembrane domain, N-linked glycosylation site or DNA-binding motif. |
| References |
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