Anti-basic FGF/FGF2 Antibody, Mouse Monoclonal sinobiological 10014-MM11

$143.00
In stock
SKU
10014-MM11
Catalog No.SizePrice (USD)
10014-MM11-5050 µL$147.96
10014-MM11-100100 µL$251.64
10014-MM11-200200 µL$355.32

General Information

Product nameAnti-basic FGF/FGF2 Antibody, Mouse Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman basic FGF/FGF2
ImmunogenRecombinant Human bFGF/FGF2 Protein (Catalog#10014-HNAE)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human bFGF/FGF2 (rh bFGF/FGF2; Catalog#10014-HNAE; NP_001997.5; Pro143-Ser288). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
SourceMonoclonal Mouse IgG1 Clone #11
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-BFGF Antibody; Anti-FGF-2 Antibody; Anti-FGFB Antibody; Anti-HBGF-2 Antibody

Background Information

Full Namefibroblast growth factor 2 (basic)
DescriptionBasic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.
Research Areas
  • Cancer Drug Targets
References
  1. Takayama S, et al. (2001) Periodontal regeneration by FGF-2 (bFGF) in primate models. J Dent Res. 80(12): 2075-9.
  2. Niu YJ, et al. (2004) Therapeutic effect of bFGF on retina ischemia-reperfusion injury. Chin Med J (Engl). 117(2): 252-7.
  3. Zhang Y, et al. (2004) Expression of aFGF, bFGF, and FGFR1 in ovarian epithelial neoplasm. Chin Med J (Engl). 117(4): 601-3.

title: Potent retro-inverso D-peptide for simultaneous targeting of angiogenic blood vasculature and tumor cells.
authors: Ying Li; Yang Lei; ...; Min Liu
journal: Bioconjugate Chemistry
date: 2013-06-24
pmid: 23241015
doi: 10.1021/bc300537z
cited_by_count: 13
techniques: Cell Culture; Modification
bioz_score: 90

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