| Catalog No. | Size | Price (USD) |
| 16124-T32-50 | 50 µL | $147.96 |
| 16124-T32-100 | 100 µL | $251.64 |
| 16124-T32-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-FGF-8 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human FGF-8 |
| Immunogen | Recombinant Human Fgf8 Protein (Catalog#16124-HNAE) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human Fgf8 (rh Fgf8; Catalog#16124-HNAE; NP_149355.1; Gln23-Arg204). Fgf8 specific IgG was purified by Human Fgf8 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AIGF Antibody; Anti-FGF-8 Antibody; Anti-FGF8 Antibody; Anti-HBGF-8 Antibody; Anti-HH6 Antibody; Anti-KAL6 Antibody
Image / Experimental Information
| Image 1 Description | Anti-FGF8a rabbit polyclonal antibody at 1:500 dilution Lane A: HepG2 Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lane C: Hela Whole Cell Lysate Lane D: NIH3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size:27 kDa Observed band size:35 kDa (We are unsure as to the identity of these extra bands.) |
| Image 1 Alt Text | Human FGF8a / FGF-8a Western blot (WB) 6743 |
| Image 1 URL | Source image |
Background Information
| Full Name | fibroblast growth factor 8 (androgen-induced) |
| Description | In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling factor, and its precise regulation is essential for embryo patterning. |
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