| Catalog No. | Size | Price (USD) |
| 200740-T10-50 | 50 µL | $147.96 |
| 200740-T10-100 | 100 µL | $251.64 |
| 200740-T10-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-BMF Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human BMF |
| Immunogen | E. coli-derived Human BMF fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human BMF fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-FLJ00065 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human BMF in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human BMF Immunohistochemistry(IHC) 24675 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human BMF in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human BMF Immunofluorescence(IF) 24676 |
| Image 2 URL | Source image |
Background Information
| Full Name | Bcl2 modifying factor |
| Description | BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. BMF is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Related Pathways |
|
| References |
|
-HD12NO0273-100-human-brain-IHC-P.png){kind=link}
-HD12NO0273-200-HeLa-IF.png){kind=link}