| Catalog No. | Size | Price (USD) |
| 11593-RP02-50 | 50 µL | $147.96 |
| 11593-RP02-100 | 100 µL | $251.64 |
| 11593-RP02-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-GBA3 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human GBA3 |
| Immunogen | Recombinant Human GBA3 protein (Catalog#11593-H08B) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human GBA3 / CBGL1 (rh GBA3; Catalog#11593-H08B; NP_066024.1; Met 1-Leu 469). GBA3 specific IgG was purified by human GBA3 affinity chromatography . |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CBG Antibody; Anti-CBGL1 Antibody; Anti-GLUC Antibody; Anti-KLRP Antibody
Background Information
| Full Name | glucosidase, beta, acid 3 (gene/pseudogene) |
| Description | Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in renal cell carcinomas and hepatocellular carcinomas. GBA3 / CBGL1 is able to hydrolyze a broad variety of glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens. GBA3 / CBGL1 possesses beta-glycosylceramidase activity and may be involved in a nonlysosomal catabolic pathway of glycosylceramide. |
| References |
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