| Catalog No. | Size | Price (USD) |
| 14568-RP01-100 | 100 µL | $147.96 |
| 14568-RP01-200 | 200 µL | $251.64 |
| 14568-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-GCSH Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human GCSH |
| Immunogen | Recombinant Human GCSH protein (Catalog#14568-H07E) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human GCSH (rh GCSH; Catalog#14568-H07E; AAA36011.1; Ser49-Glu173). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-GCE Antibody; Anti-MMDS7 Antibody; Anti-NKH Antibody
Background Information
| Full Name | glycine cleavage system protein H (aminomethyl carrier) |
| Description | Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). GCSH is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in GCSH gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for GCSH gene. Also, several transcribed and non-transcribed pseudogenes of GCSH gene exist throughout the genome. |
| References |
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