| Catalog No. | Size | Price (USD) |
| 100140-R012-50 | 50 µL | $177.58 |
| 100140-R012-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-GFAP Antibody, Rabbit Monoclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human GFAP |
| Immunogen | A synthetic peptide corresponding to the center region of the human GFAP |
| Preparation | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the human GFAP. |
| Source | Monoclonal Rabbit IgG Clone #012 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-ALXDRD Antibody; Anti-FLJ45472 Antibody
Image / Experimental Information
| Image 1 Description | Anti-GFAP rabbit monoclonal antibody at 1:500 dilution Lane A: Mouse brain tissue lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size:50 kDa Observed band size:45 kDa |
| Image 1 Alt Text | Human GFAP Western blot (WB) 6433 |
| Image 1 URL | Source image |
Background Information
| Full Name | glial fibrillary acidic protein |
| Description | GFAP is a cell-specific marker which belongs to the intermediate filament family. It can distinguish astrocytes from other glial cells during development. GFAP is expressed in cells lacking fibronectin. It is a type III intermediate filaments protein which contains three domains: the head, rod and tail domains. GFAP functions in many important entral nervous system (CNS) processes, including cell communication and the functioning of the blood brain barrier. Improper GFAP regulation can cause multiple disorders. Defects in GFAP is related to Alexander disease which is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes. |
| Research Areas |
|
| References |
|
