| Catalog No. | Size | Price (USD) |
| 10701-R009-P-25 | 25 Tests | $103.68 |
| 10701-R009-P-100 | 100 Tests | $222.17 |
General Information
| Product name | Recombinant Anti-GM-CSF Receptor alpha Antibody (PE), Rabbit Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human GM-CSF Receptor alpha |
| Immunogen | Recombinant Human CD116 / GM-CSFR protein (Catalog#10701-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD116 / GM-CSFR (rh CD116 / GM-CSFR; Catalog#10701-H08H; P15509-1; Met1-Gly320) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Source | Monoclonal Rabbit IgG Clone #009 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Concentration | 10 μl/Test, 0.1 mg/ml |
| Conjugate | PE |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Synonyms: Anti-alphaGMR Antibody; Anti-CD116 Antibody; Anti-CDw116 Antibody; Anti-CSF2R Antibody; Anti-CSF2RAX Antibody; Anti-CSF2RAY Antibody; Anti-CSF2RX Antibody; Anti-CSF2RY Antibody; Anti-GM-CSF-R-alpha Antibody; Anti-GMCSFR Antibody; Anti-GMCSFR-alpha Antibody; Anti-GMR Antibody; Anti-GMR-alpha Antibody; Anti-SMDP4 Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of anti-human GM-CSFRa(CD116) on human peripheral blood monocytes. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable monocytes. |
| Image 1 Alt Text | Human CD116/GM-CSFR Flow Cytometry (FC) 5100 |
| Image 1 URL | Source image |
Background Information
| Full Name | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| Description | CD116/GM-CSFR has been preferentially associated with M4, M5 subtype of AML but is not specific. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD116/GM-CSFR is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. CD116/GM-CSFR is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. |
| References |
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