Anti-GPR37 Antibody, Rabbit Polyclonal sinobiological 13496-RP01

$143.00
In stock
SKU
13496-RP01
Catalog No.SizePrice (USD)
13496-RP01-100100 µL$147.96
13496-RP01-200200 µL$251.64
13496-RP01-400400 µL$355.32

General Information

Product nameAnti-GPR37 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman GPR37
ImmunogenRecombinant Human GPR37 Protein (Catalog#13496-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human GPR37 (rh GPR37; Catalog#13496-H08H; NP_005293.1; Met1-Met265). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-EDNRBL Antibody; Anti-hET(B)R-LP Antibody; Anti-PAELR Antibody

Background Information

Full NameG protein-coupled receptor 37 (endothelin receptor type B-like)
DescriptionGPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family comprised of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. They only exist in eukaryotes, including yeast, choanoflagellates, and animals. These receptors are bonded and activated by light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters. These ligands vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases and are also the target of approximately 40% of all modern medicinal drugs. GPR37 is expressed in the brain and spinal cord, and at lower levels in the testis, placenta, and liver, but no detectable expression is observed in any other tissue. GPR37 may have a unique functional role in the central nervous system.
References
  1. Marazziti D, et al. (1997) Cloning of GPR37, a gene located on chromosome 7 encoding a putative G-protein-coupled peptide receptor, from a human frontal brain EST library. Genomics. 45(1):68-77.
  2. Imai, et al. (2002) CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol Cell. 10(1):55-67.
  3. Imai, et al. (2001) An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell. 105(7):891-902.

Reviews

Write Your Own Review
You're reviewing:Anti-GPR37 Antibody, Rabbit Polyclonal sinobiological 13496-RP01
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.