E. coli-derived Human GSR/Glutathione reductase fragment
Preparation
Produced in rabbits immunized with E. coli-derived Human GSR/Glutathione reductase fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Anti-GSR/Glutathione reductase rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: Jurkat Whole Cell Lysate Lane D: A549 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:56 kDa Observed band size:54 kDa
Image 1 Alt Text
Human GSR/Glutathione reductase Western blot (WB) 45568
Anti-GSR/Glutathione reductase rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: Jurkat Whole Cell Lysate Lane D: A549 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:56 kDa Observed band size:54 kDa
Image 2 Alt Text
Human GSR/Glutathione reductase Immunohistochemistry(IHC) 45569
Anti-GSR/Glutathione reductase rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: Jurkat Whole Cell Lysate Lane D: A549 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:56 kDa Observed band size:54 kDa
Image 3 Alt Text
Human GSR/Glutathione reductase Immunohistochemistry(IHC) 45570
GSR (Glutathione-Disulfide Reductase) is a Protein Coding gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. GSR, a key member of the glutathione antioxidant defense system, converts oxidized glutathione (GSSG) to reduced glutathione (GSH) and maintains the intracellular glutathione redox state to protect the cells from oxidative damage. It is a central enzyme of cellular antioxidant defense. Under normal physiological conditions, GSR is not essential for the maintenance of antioxidant defenses in the mouse cochlea. The antioxidant enzyme GSR gene polymorphisms are significantly associated with bone mineral density (BMD). Diseases associated with GSR include Hemolytic Anemia Due To Glutathione Reductase Deficiency and Riboflavin Deficiency.