Anti-GSTZ1 Antibody, Rabbit Polyclonal sinobiological 14237-RP01

$143.00
In stock
SKU
14237-RP01
Catalog No.SizePrice (USD)
14237-RP01-100100 µL$147.96
14237-RP01-200200 µL$251.64
14237-RP01-400400 µL$355.32

General Information

Product nameAnti-GSTZ1 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman GSTZ1
ImmunogenRecombinant Human GSTZ1 protein (Catalog#14237-H07E)
PreparationProduced in rabbits immunized with purified, recombinant Human GSTZ1 (rh GSTZ1; Catalog#14237-H07E; NP_665877.1; Met1-Ala216). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-GSTZ1-1 Antibody; Anti-MAAI Antibody; Anti-MAAID Antibody; Anti-MAI Antibody

Background Information

Full Nameglutathione S-transferase zeta 1
DescriptionGSTZ1 (Glutathione S-Transferase Zeta 1) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. GSTZ1 gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. GSTZ1 is a bifunctional protein that has minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. GSTZ1 catalyzes the glutathione-dependent oxygenation of dichloroacetic acid to glyoxylic acid. GSTZ1 participates in the catabolism of phenylalanine and tyrosine. Thus defects in GSTZ1 cause harsh metabolic disorders including alkaptonuria, phenylketonuria, and tyrosinemia.
References
  1. Tong Z. et al., 1999, Chem Res Toxicol. 11 (11): 1332-8.
  2. Tong Z. et al., 1999, Biochem J. 331 (2): 371-4.
  3. Ketterer B. 2001, Chem Biol Interact. 138 (1): 27-42.

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