Anti-HSP70 Antibody, Rabbit Polyclonal sinobiological 11660-T46
$243.00
In stock
SKU
11660-T46
| Catalog No. | Size | Price (USD) |
| 11660-T46-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-HSP70 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human HSP70 |
| Immunogen | Recombinant Human HSP70 Protein (Catalog#11660-H07B) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human HSP70 (rh HSP70; Catalog#11660-H07B; NP_005337.2; Ala2-Asp641). HSP70 specific IgG was purified by Human HSP70 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-HEL-S-103 Antibody; Anti-HSP70 Antibody; Anti-HSP70-1 Antibody; Anti-HSP70-1A Antibody; Anti-HSP70-2 Antibody; Anti-HSP70.1 Antibody; Anti-HSP70.2 Antibody; Anti-HSP70I Antibody; Anti-HSP72 Antibody; Anti-HSPA1 Antibody; Anti-HSX70 Antibody
Image / Experimental Information
| Image 1 Description | Anti-HSP70 rabbit polyclonal antibody at 1:10000 dilution Lane A: Hela Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size:70 kDa Observed band size:70 kDa |
| Image 1 Alt Text | Human HSP70 Western blot (WB) 46767 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-HSP70 rabbit polyclonal antibody at 1:10000 dilution Lane A: Hela Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size:70 kDa Observed band size:70 kDa |
| Image 2 Alt Text | Human HSP70 Immunohistochemistry(IHC) 46768 |
| Image 2 URL | Source image |
| Image 3 Description | Anti-HSP70 rabbit polyclonal antibody at 1:10000 dilution Lane A: Hela Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size:70 kDa Observed band size:70 kDa |
| Image 3 Alt Text | Human HSP70 Immunohistochemistry(IHC) 46769 |
| Image 3 URL | Source image |
| Image 4 Description | Anti-HSP70 rabbit polyclonal antibody at 1:10000 dilution Lane A: Hela Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size:70 kDa Observed band size:70 kDa |
| Image 4 Alt Text | Human HSP70 Immunohistochemistry(IHC) 46770 |
| Image 4 URL | Source image |
| Image 5 Description | Anti-HSP70 rabbit polyclonal antibody at 1:10000 dilution Lane A: Hela Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size:70 kDa Observed band size:70 kDa |
| Image 5 Alt Text | Human HSP70 Immunofluorescence(IF) 46771 |
| Image 5 URL | Source image |
Background Information
| Full Name | heat shock 70kDa protein 1A |
| Description | HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. HSP are abundant and conserved proteins present in all cells. Upon temperature shock or other stress stimuli, HSP is synthesized intracellularly, which may protect cells from protein denaturation or death. Extracellularly, HSP can serve a cytokine function to initiate both innate and adaptive immunity through activation of APC. HSP serves also a chaperone function and facilitates the presentation of antigen peptide to T cells. Molecular chaperones of the Hsp70 family have diverse functions in cells. They assist the folding of newly synthesized and stress-denatured proteins, as well as the import of proteins into organelles, and the dissociation of aggregated proteins. The well-conserved Hsp70 chaperones are ATP dependent: binding and hydrolysis of ATP regulate their interactions with unfolded polypeptide substrates, and ATPase cycling is necessary for their function. All cellular functions of Hsp70 chaperones use the same mechanism of ATP-driven polypeptide binding and release. |
| Related Pathways |
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