| Catalog No. | Size | Price (USD) |
| 14227-MM05-50 | 50 µL | $147.96 |
| 14227-MM05-100 | 100 µL | $251.64 |
| 14227-MM05-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Iba1 Antibody, Mouse Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Iba1 No cross-reactivity in ELISA with E.coli cell lysate |
| Immunogen | Recombinant Human IBA1 / AIF1 protein (Catalog#14227-H07E) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IBA1 / AIF1 (rh IBA1 / AIF1; Catalog#14227-H07E; P55008-1; Met1-Pro147). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| Source | Monoclonal Mouse IgG2a Clone #05 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AIF-1 Antibody; Anti-Em:AF129756.17 Antibody; Anti-G1 Antibody; Anti-IBA1 Antibody; Anti-IRT-1 Antibody; Anti-IRT1 Antibody
Background Information
| Full Name | allograft inflammatory factor 1 |
| Description | AIF1, also known as IBA1, is an actin-binding protein. AIF1 is expressed selectively in human macrophage-like cell lines, and in a subset of CD68(+) macrophages in the interstitial and perivascular spaces of human heart allografts. It is expressed in macrophages and neutrophils. AIF1 enhances membrane ruffling and RAC activation. AIF1 enhances the actin-bundling activity of LCP1. It also enhances lymphocyte migration. AIF1 may play a role in macrophage activation and function. It binds calcium and plays a role in RAC signaling and in phagocytosis. It promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. |
| Research Areas |
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| References |
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title: Ginsenoside Rg3 attenuates neuroinflammation and hippocampal neuronal damage after traumatic brain injury in mice by inactivating the NF-kB pathway via SIRT1 activation.
authors: Xi Liu; Jia Gu; ...; Bo Li
journal: Cell cycle (Georgetown, Tex.)
date: 2024-07-05
pmid: 38796716
doi: 10.1080/15384101.2024.2355008
cited_by_count: 7
techniques: Fluorescence; Incubation; Microscopy; Staining
bioz_score: 92
