| Catalog No. | Size | Price (USD) |
| 10332-RP02-50 | 50 µL | $147.96 |
| 10332-RP02-100 | 100 µL | $251.64 |
| 10332-RP02-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-ICAM-2/CD102 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human ICAM-2/CD102 |
| Immunogen | Recombinant Human ICAM-2 / CD102 protein (Catalog#10332-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human ICAM-2 / CD102 (rh ICAM-2 / CD102; Catalog#10332-H08H; NP_000864.2; Met 1-Gln 223). ICAM-2 / CD102 specific IgG was purified by Human ICAM-2 / CD102 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD102 Antibody
Image / Experimental Information
| Image 1 Description | ICAM2 was immunoprecipitated using: Lane A:0.5 mg Hela Whole Cell Lysate 0.5 µL anti-ICAM2 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein G. Primary antibody: Anti-ICAM2 rabbit polyclonal antibody,at 1:500 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 31 kDa Observed band size: 31 kDa |
| Image 1 Alt Text | Human ICAM-2/CD102 Immunoprecipitation(IP) 6160 |
| Image 1 URL | Source image |
| Image 2 Description | ICAM2 was immunoprecipitated using: Lane A:0.5 mg Hela Whole Cell Lysate 0.5 µL anti-ICAM2 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein G. Primary antibody: Anti-ICAM2 rabbit polyclonal antibody,at 1:500 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 31 kDa Observed band size: 31 kDa |
| Image 2 Alt Text | Human ICAM-2/CD102 Western blot (WB) 13186 |
| Image 2 URL | Source image |
Background Information
| Full Name | intercellular adhesion molecule 2 |
| Description | Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment. |
| References |
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