| Catalog No. | Size | Price (USD) |
| 10139-T16-50 | 50 µL | $147.96 |
| 10139-T16-100 | 100 µL | $251.64 |
| 10139-T16-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-IL-1 beta Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IL-1 beta |
| Immunogen | Recombinant Human IL1B / IL-1B / IL-1 beta Protein (Catalog#10139-HNAE) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human IL1B / IL-1B / IL-1 beta (rh IL1B / IL-1B / IL-1 beta; Catalog#10139-HNAE; NP_000567.1; Ala117-Ser269). IL1B / IL-1B / IL-1 beta specific IgG was purified by Human IL1B / IL-1B / IL-1 beta affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-IL-1 Antibody; Anti-IL-1B Antibody; Anti-IL1-BETA Antibody; Anti-IL1beta Antibody; Anti-IL1F2 Antibody
Background Information
| Full Name | interleukin 1, beta |
| Description | Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair in the cortex. The IL1 superfamily consists of three members, IL1A (IL1 alpha), IL1B (IL1 beta), and IL1 receptor antagonist (IL1Ra). In clinical, it has been reported that Interleukin (IL)-1 may influence Th1 / Th2 immune responsiveness and has been implicated in the establishment of a successful pregnancy. Proinflammatory interleukin (IL)-1 gene polymorphisms associated with high levels of IL-1beta activity increase the risk for hypochlorhydria and distal gastric carcinoma. IL1B polymorphisms may be involved in susceptibility to SSc. Moreover, the IL2-384-G allele may be a marker for the limited phenotype of systemic sclerosis (SSc). |
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| References |
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title: Inhibiting thromboinflammation with a designed peptide that blocks the IL-1β-FXIa axis uncouples antithrombosis from bleeding risk
authors: Yuewei Wang; Qikai Yin; ...; Xiaopeng Tang
journal: Cellular and Molecular Life Sciences: CMLS
date: 2026-04-15
pmid: 41984107
doi: 10.1007/s00018-026-06205-1
cited_by_count: 0
techniques: Activity Assay; Binding Assay; Clinical Proteomics; Coagulation; Imaging; Immunoprecipitation; Incubation; Inhibition; Injection; Negative Control; Polyacrylamide Gel Electrophoresis; Pull Down Assay; SDS Page; Saline; Sequencing; Staining; Western Blot
bioz_score: 95
title: Depletion of IGFALS Serum Level up to 3 Months After Cardiac Surgery, with Exploration of Potential Relationships to Surrogates of Organ Failures and Clinical Outcomes
authors: Krzysztof Laudanski; Mohamed A. Mahmoud; ...; Wenqiang Fan
journal: Current Issues in Molecular Biology
date: 2025-07-23
doi: 10.3390/cimb47080581
cited_by_count: 0
techniques: Bead-based Assay; Enzyme-linked Immunosorbent Assay; Isolation; Virus
bioz_score: 95
title: Pharmacological network analysis of the functions and mechanism of kaempferol from Du Zhong in intervertebral disc degeneration (IDD).
authors: Xiaobin Wang; Yanlin Tan; ...; Jing Li
journal: Journal of Orthopaedic Translation
date: 2023-03-01
pmid: 36909862
cited_by_count: 20
techniques: Cell Culture; In Vitro
bioz_score: 95
title: Shuxie-1 Decoction Alleviated CUMS -Induced Liver Injury via IL-6/JAK2/STAT3 Signaling
authors: Mengting Zhang; Wanhong Wu; ...; Shuyu Yang
journal: Frontiers in Pharmacology
date: 2022-04-06
pmid: 35462928
doi: 10.3389/fphar.2022.848355
pmcid: 9019685
cited_by_count: 11
techniques: Blocking Assay; Incubation; Polymerase Chain Reaction; Real-time Polymerase Chain Reaction; SYBR Green Assay; Western Blot
bioz_score: 95
title: PAI-1 augments mucosal damage in colitis
authors: Gerard E Kaiko; Feidi Chen; ...; Thaddeus S Stappenbeck
journal: Science translational medicine
date: 2019-09-20
pmid: 30842312
doi: 10.1126/scitranslmed.aat0852
pmcid: 6779314
cited_by_count: 45
techniques: Concentration Assay; Incubation; Protease Inhibitor; Recombinant
bioz_score: 95
title: Protein Kinase Serine/Threonine Kinase 24 Positively Regulates Interleukin 17-Induced Inflammation by Promoting IKK Complex Activation
authors: Yu Jiang; Miao Tian; ...; Xiaojian Wang
journal: Frontiers in Immunology
date: 2018-04-30
pmid: 29760709
doi: 10.3389/fimmu.2018.00921
pmcid: 5936754
cited_by_count: 17
techniques: Recombinant
bioz_score: 95
