Anti-C10orf4/FRA10AC1 Antibody, Rabbit Polyclonal sinobiological 207066-T36

$143.00
In stock
SKU
207066-T36
Catalog No.SizePrice (USD)
207066-T36-5050 µL$147.96
207066-T36-100100 µL$251.64
207066-T36-200200 µL$355.32

General Information

Product nameAnti-C10orf4/FRA10AC1 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman C10orf4/FRA10AC1
ImmunogenE. coli-derived Human C10orf4 / FRA10AC1 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human C10orf4 / FRA10AC1 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-C10orf4 Antibody; Anti-F26C11.1-like Antibody; Anti-FRA10A Antibody; Anti-NEDGFC Antibody; Anti-PRO2972 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-C10orf4/FRA10AC1 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lane C: NIH/3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:37 kDa Observed band size:40 kDa
Image 1 Alt TextHuman C10orf4/FRA10AC1 Western blot (WB) 34784
Image 1 URLSource image
Image 2 DescriptionAnti-C10orf4/FRA10AC1 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lane C: NIH/3T3 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:37 kDa Observed band size:40 kDa
Image 2 Alt TextHuman C10orf4/FRA10AC1 Immunoprecipitation(IP) 34785
Image 2 URLSource image

Background Information

Full Namefragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
DescriptionThe FRA10AC1 gene contains a tandem CGG repeat region within a CpG island that normally consists of 8-14 repeats but can expand to over 200 repeats. The major FRA10AC1 transcript encodes a deduced 315-amino acid protein with a calculated molecular mass of 37.5 kD. FRA10AC1 contains several sites for serine phosphorylation and a bipartite nuclear localization signal embedded within a larger lysine-rich region. The FRA10AC1 protein is conserved between species. The human protein shares 86% identity with mouse Fra10ac1 and about 35% identity with plant and C. elegans Fra10ac1. A central sequence of FRA10AC1 is most highly conserved. The FRA10AC1 gene is found within the rare FRA10A folate-sensitive fragile site.
References
  1. Sarafidou T, et al. (2004) Folate-sensitive fragile site fra10a is due to an expansion of a cgg repeat in a novel gene, fra10ac1, encoding a nuclear protein. Genomics 84 (1): 69-81.
  2. De Leon-Luis J, et al. (2005) Prenatal diagnosis of fra10a: A case report and literature review. Am J Med Genet A 136 (1): 63-65.

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