| Catalog No. | Size | Price (USD) |
| 13060-RP01-100 | 100 µL | $147.96 |
| 13060-RP01-200 | 200 µL | $251.64 |
| 13060-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-IL-20 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IL-20 |
| Immunogen | Recombinant Human Interleukin-20 / IL20 Protein (Catalog#13060-HNAE) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human Interleukin-20 / IL20 (rh Interleukin-20 / IL20; Catalog#13060-HNAE; Q9NYY1; Leu25-Glu176). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-IL-20 Antibody; Anti-IL10D Antibody; Anti-UNQ852/PRO1801 Antibody; Anti-ZCYTO10 Antibody
Background Information
| Full Name | interleukin 20 |
| Description | IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. It has been shown that interleukin-20 transduces its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates the proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. Also, IL20/Interleukin-20 also causes cell expansion of multipotential hematopoietic progenitor cells. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. |
| References |
|
