Anti-IL-33 Antibody, Mouse Monoclonal sinobiological 10368-MM02

$143.00
In stock
SKU
10368-MM02
Catalog No.SizePrice (USD)
10368-MM02-5050 µL$147.96
10368-MM02-100100 µL$251.64
10368-MM02-200200 µL$355.32

General Information

Product nameAnti-IL-33 Antibody, Mouse Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman IL-33 No cross-reactivity in ELISA with E.coli cell lysate
ImmunogenRecombinant Human IL-33 protein (Catalog#10368-HNAE)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-33 (rh IL-33; Catalog#10368-HNAE; NP_254274.1; Ser 112-Thr 270). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography .
SourceMonoclonal Mouse IgG2a Clone #1D11C3F3
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-C9orf26 Antibody; Anti-DKFZp586H0523 Antibody; Anti-DVS27 Antibody; Anti-IL1F11 Antibody; Anti-NF-HEV Antibody; Anti-NFEHEV Antibody; Anti-NFHEV Antibody

Background Information

Full Nameinterleukin 33
DescriptionInterleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyer's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.
Related Pathways
  • IL1 signaling pathway
References
  1. Iikura M, et al. (2007) IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest. 87(10): 971-8.
  2. Lamkanfi M, et al. (2009) IL-33 raises alarm. Immunity. 31(1): 5-7.

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