| Catalog No. | Size | Price (USD) |
| 10895-R004-F-25 | 25 Tests | $133.30 |
| 10895-R004-F-100 | 100 Tests | $414.71 |
General Information
| Product name | Recombinant Anti-IL-17RA Antibody (FITC), Rabbit Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IL-17RA |
| Immunogen | Recombinant Human IL17RA/IL-17RA/CD217 Protein (Catalog#10895-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL17RA/IL-17RA/CD217 (rh IL17RA/IL-17RA/CD217; Catalog#10895-H08H; NP_055154.3; Met1-Trp320) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Source | Monoclonal Rabbit IgG Clone #004 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Concentration | 10 μl/Test, 0.1 mg/ml |
| Conjugate | FITC |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Synonyms: Anti-CANDF5 Antibody; Anti-CD217 Antibody; Anti-CDw217 Antibody; Anti-hIL-17R Antibody; Anti-IL-17RA Antibody; Anti-IL17R Antibody; Anti-IMD51 Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of Human IL17RA(CD217) expression on human whole blood granulocytes. Cells were stained with FITC-conjugated anti-Human IL17RA(CD217). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. |
| Image 1 Alt Text | Human IL17RA/IL-17RA/CD217 Flow Cytometry (FC) 17077 |
| Image 1 URL | Source image |
Background Information
| Full Name | interleukin 17 receptor A |
| Description | Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. |
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| References |
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