| Catalog No. | Size | Price (USD) |
| 13091-T16-50 | 50 µL | $147.96 |
| 13091-T16-100 | 100 µL | $251.64 |
| 13091-T16-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-IL-17RB Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IL-17RB |
| Immunogen | Recombinant Human IL17BR / IL17RB / IL-17 Receptor B Protein (Catalog#13091-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human IL17BR / IL17RB / IL-17 Receptor B (rh IL17BR / IL17RB / IL-17 Receptor B; Catalog#13091-H08H; NP_061195.2; Met1-Gly289). IL17BR / IL17RB / IL-17 Receptor B specific IgG was purified by Human IL17BR / IL17RB / IL-17 Receptor B affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CRL4 Antibody; Anti-EVI27 Antibody; Anti-IL17BR Antibody; Anti-IL17RH1 Antibody; Anti-UNQ2501/PRO19612 Antibody
Background Information
| Full Name | interleukin 17 receptor B |
| Description | IL17RB (Interleukin 17 Receptor B) is a Protein Coding gene. IL17RB is the receptor for IL17E, the only member of the IL17 family promoting Th2 reactions. IL17RB is induced on human macrophages by IL4 and enhanced by TGFbeta. Overexpression of IL17RB is associated with poor prognosis and the short survival of breast cancer patients.IL17RB/IL17B signaling triggers a substantial increase in cell growth, proliferation, and migration through the activation of NF-kappaB as well as the up-regulation of the Bcl-2. IL17RB may be the only gene expressed in CD4+ T cells whose transcript measurement is correlated with the variation in IgE level in asthmatics. Diseases associated with IL17RB include Chronic Mucocutaneous Candidiasis and Seborrheic Infantile Dermatitis. |
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