Anti-IL-17RC Antibody, Rabbit Polyclonal sinobiological 11747-RP01

$143.00
In stock
SKU
11747-RP01
Catalog No.SizePrice (USD)
11747-RP01-100100 µL$147.96
11747-RP01-200200 µL$251.64
11747-RP01-400400 µL$355.32

General Information

Product nameAnti-IL-17RC Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman IL-17RC
ImmunogenRecombinant Human IL17RC protein (Catalog#11747-H08B)
PreparationProduced in rabbits immunized with purified, recombinant Human IL17RC (rh IL17RC; Catalog#11747-H08B; NP_116121.2; Met 1-Ala 454). Total IgG was purified by Protein A affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CANDF9 Antibody; Anti-IL17-RL Antibody; Anti-IL17RL Antibody; Anti-UNQ6118/PRO20040/PRO38901 Antibody

Background Information

Full Nameinterleukin 17 receptor C
DescriptionIL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the prostate, skin, and other tissues. The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies before clinical application. methylation of IL17RC could play as a marker in choroidal neovascularization (CNV) and degeneration of retinal pigment epithelium (RPE) cells in vitro. Diseases associated with IL17RC include Candidiasis, Familial, 9, and Chronic Mucocutaneous Candidiasis.
Related Pathways
  • IL17 signaling pathway
References
  1. Allen W, et al. (2010) IL-17RC: A partner in IL-17 signaling and beyond. Semin Immunopathol. 32(1): 33-42.
  2. You ZB, et al. (2007) Differential Expression of IL-17RC Isoforms in Androgen-Dependent and Androgen-Independent Prostate Cancers1. Neoplasia. 9(6): 464-70.
  3. Zrioual S, et al. (2008) IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood. J Immunol. 180(1): 655-63.
  4. Kuestner RE, et al. (2010) Identification of the IL-17 Receptor Related Molecule IL-17RC as the Receptor for IL-17F. J Immunol.179(8): 5462-73.

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