Anti-C21orf2 Antibody, Rabbit Polyclonal sinobiological 205710-T08

$143.00
In stock
SKU
205710-T08
Catalog No.SizePrice (USD)
205710-T08-5050 µL$147.96
205710-T08-100100 µL$251.64
205710-T08-200200 µL$355.32

General Information

Product nameAnti-C21orf2 Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman C21orf2
ImmunogenE. coli-derived Human C21orf2 / CFAP410 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human C21orf2 / CFAP410 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-A2 Antibody; Anti-C21orf2 Antibody; Anti-LRRC76 Antibody; Anti-RDMS Antibody; Anti-SMDAX Antibody; Anti-YF5 Antibody; Anti-YF5/A2 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human C21orf2 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman C21orf2 Immunohistochemistry(IHC) 26061
Image 1 URLSource image

Background Information

DescriptionCFAP410 (Cilia And Flagella Associated Protein 410) is a Protein Coding gene. Diseases associated with CFAP410 include Retinal Dystrophy With Or Without Macular Staphyloma and Spondylometaphyseal Dysplasia, Axial. CFAP410 interacted with NEK1,a kinase involved in DNA damage response. Knockdown of C21ORF2 caused defective DNA repair via homologous recombination, but not nonhomologous end joining, and C21ORF2-knockdown cells did not show defective activation of G2-phase DNA damage checkpoint. CFAP410 plays a role in the regulation of cell morphology and cytoskeletal organization. CFAP410 is necessary for maintenance of the differentiated chondrocyte phenotype.

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