| Catalog No. | Size | Price (USD) |
| 12341-MM13-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-Interferon alpha 1/IFNA1 Antibody, Mouse Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Interferon alpha 1/IFNA1 |
| Immunogen | Recombinant Human Interferon alpha 1/IFNA1 Protein (Catalog# 12341-H08Y) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Interferon alpha 1/IFNA1 (rh Interferon alpha 1/IFNA1; Catalog#12341-H08Y; NP_076918.1; Cys24-Glu189). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG2a Clone #13 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-IFL Antibody; Anti-IFN Antibody; Anti-IFN-ALPHA Antibody; Anti-IFN-alphaD Antibody; Anti-IFNA13 Antibody; Anti-IFNA@ Antibody; Anti-leIF D Antibody
Background Information
| Full Name | interferon, alpha 1 |
| Description | IFNA1, also known as IFN-alpha and IFNA, belongs to the alpha/beta interferon family. Interferons(IFNs) are proteins made and released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites, or tumor cells. They belong to the large class of glycoproteins known as cytokines. IFNs stimulate the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. IFNs can activate immune cells, such as natural killer cells and macrophages; they increase recognition of infection or tumor cells by up-regulating antigen presentation to T lymphocytes, and they also increase the ability of uninfected host cells to resist new infection by the virus. Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon is produced by mitogen- or antigen-stimulated T lymphocytes. IFNA1 is produced by macrophages and has antiviral activities. |
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