Recombinant Anti-interferon-alpha/IFNA5 Antibody, Rabbit Monoclonal sinobiological 10342-R102

$1,900.00
In stock
SKU
10342-R102
Catalog No.SizePrice (USD)
10342-R102-11 mL$1,969.87
10342-R102-2020 µL$118.49
10342-R102-5050 µL$177.58
10342-R102-100100 µL$340.51

General Information

Product nameRecombinant Anti-interferon-alpha/IFNA5 Antibody, Rabbit Monoclonal
Validated applicationsELISA(Cap) (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman interferon-alpha/IFNA5
ImmunogenRecombinant Human IFNA5/IFNaG Protein (Catalog#10342-H08H)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human IFNA5/IFNaG (rh IFNA5/IFNaG; Catalog#10342-H08H; P01569; Met1-Glu189).
SourceMonoclonal Rabbit IgG Clone #102
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-IFN-alpha-5 Antibody; Anti-IFN-alphaG Antibody; Anti-INA5 Antibody; Anti-INFA5 Antibody; Anti-leIF G Antibody

Background Information

Full Nameinterferon, alpha 5
DescriptionInterferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation.
References
  1. Lau JY, et al. (1993) Discrepancy between biochemical and virological responses to interferon-alpha in chronic hepatitis C. Lancet. 342(8881): 1208-9.
  2. Kessler DS, et al. (1990) Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev. 4(10): 1753-65.
  3. Gutterman JU. Cytokine therapeutics: lessons from interferon alpha. Proc Natl Acad Sci U S A. 91(4): 1198-205.

Reviews

Write Your Own Review
You're reviewing:Recombinant Anti-interferon-alpha/IFNA5 Antibody, Rabbit Monoclonal sinobiological 10342-R102
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.