| Catalog No. | Size | Price (USD) |
| 11725-R209-1 | 1 mL | $1,969.87 |
| 11725-R209-20 | 20 µL | $118.49 |
| 11725-R209-50 | 50 µL | $177.58 |
| 11725-R209-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-IFN gamma Antibody, Rabbit Monoclonal |
| Validated applications | ELISA(Det) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IFN gamma |
| Immunogen | Recombinant Human Interferon Gamma/IFN gamma/IFNG Protein (Catalog#11725-HNAS) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human Interferon Gamma/IFN gamma/IFNG (rh Interferon Gamma/IFN gamma/IFNG; Catalog#11725-HNAS; NP_000610.2; Met1-Gln166). |
| Source | Monoclonal Rabbit IgG Clone #209 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-IFG Antibody; Anti-IFI Antibody; Anti-IMD69 Antibody
Background Information
| Full Name | interferon, gamma |
| Description | IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity. |
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| References |
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title: Yes-associated protein regulates autophagy to restore skin barrier function in atopic dermatitis
authors: Jinjing Jia; Xin Ma; ...; Xiumei Mo
journal: Frontiers in Immunology
date: 2025-11-19
doi: 10.3389/fimmu.2025.1681148
cited_by_count: 0
techniques: Cell Culture; Knockdown; Modification; Over Expression; Plasmid Preparation; Transfection
bioz_score: 93
