Produced in rabbits immunized with E. coli-derived Human C5orf22 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Synonyms: Anti-FLJ11193 Antibody
Image / Experimental Information
Image 1 Description
Immunochemical staining of human C5orf22 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
C5orf22 (Chromosome 5 Open Reading Frame 22) is located on human chromosome 5p13.3. The C5orf22 protein is ubiquitously expressed in brain, colon, urinary bladder and other tissues. The C5orf22 (also known as FLJ11193) gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, zebrafish, fruit fly, mosquito, and frog. 245 organisms have orthologs with human gene C5orf22. C5orf22 is a component of the WBP11/PQBP1 splicing complex. Depletion of C5orf22 leads to the aberrant splicing and expression of genes involved in cell growth and immunomodulation.
References
Zi Z, et al. (2020) A proteomic connectivity map for characterizing the tumor adaptive response to small molecule chemical perturbagens. ACS Chem Biol 15 (1): 140-150.