Recombinant Anti-LAIR2 Antibody, Rabbit Monoclonal sinobiological 10868-R001

$1,900.00
In stock
SKU
10868-R001
Catalog No.SizePrice (USD)
10868-R001-11 mL$1,969.87
10868-R001-2020 µL$118.49
10868-R001-5050 µL$177.58
10868-R001-100100 µL$340.51

General Information

Product nameRecombinant Anti-LAIR2 Antibody, Rabbit Monoclonal
Validated applicationsELISA(Cap) (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman LAIR2
ImmunogenRecombinant Human LAIR2 (CD306) Protein (Catalog#10868-H08H)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human LAIR2 (CD306) (rh LAIR2 (CD306); Catalog#10868-H08H; NP_002279.2; Met1-Pro152).
SourceMonoclonal Rabbit IgG Clone #001
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CD306 Antibody; Anti-LAIR-2 Antibody

Background Information

Full Nameleukocyte associated immunoglobulin like receptor 2
DescriptionLeukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one Ig-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.
Research Areas
  • ITIM/ITAM Immunoreceptors and Related Molecules
References
  1. Meyaard, L. et al.,1997, Immunity.7:283-290.
  2. Meyaard, L. et al.,1999, J. Immunol. 162:5800-5804.
  3. Meyaard, L. et al., 2001, J. Exp. Med. 194 (1): 107-112.
  4. Meyaard, L., 2003, J Biol Regul Homeost Agents. 17 (4): 330-333.
  5. Lebbink, R. J. et al., 2008, J Immunol. 180 (3):1662-1669.
  6. Lebbink,R.J. et al., 2009, Matrix Biol. 28 (4):202-210.

Reviews

Write Your Own Review
You're reviewing:Recombinant Anti-LAIR2 Antibody, Rabbit Monoclonal sinobiological 10868-R001
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.