Anti-CACNA2D1 Antibody, Rabbit Polyclonal sinobiological 202658-T44
$243.00
In stock
SKU
202658-T44
| Catalog No. | Size | Price (USD) |
| 202658-T44-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-CACNA2D1 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CACNA2D1 |
| Immunogen | E. coli-derived Human CACNA2D1 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CACNA2D1 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-alpha2delta-1 Antibody; Anti-CACNA2 Antibody; Anti-CACNL2A Antibody; Anti-CCHL2A Antibody; Anti-DEE110 Antibody; Anti-LINC01112 Antibody; Anti-lncRNA-N3 Antibody; Anti-MHS3 Antibody
Image / Experimental Information
| Image 1 Description | CACNA2D1 was immunoprecipitated using: Lane A:0.5 mg SHSY-5Y Whole Cell Lysate Lane B:0.5 mg U87-MG Whole Cell Lysate 4 µL anti-CACNA2D1 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein A/G. Primary antibody: Anti-CACNA2D1 rabbit polyclonal antibody,at 1:100 dilution Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 125 kDa Observed band size :125 kDa |
| Image 1 Alt Text | Human CACNA2D1 Immunoprecipitation(IP) 37255 |
| Image 1 URL | Source image |
| Image 2 Description | CACNA2D1 was immunoprecipitated using: Lane A:0.5 mg SHSY-5Y Whole Cell Lysate Lane B:0.5 mg U87-MG Whole Cell Lysate 4 µL anti-CACNA2D1 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein A/G. Primary antibody: Anti-CACNA2D1 rabbit polyclonal antibody,at 1:100 dilution Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 125 kDa Observed band size :125 kDa |
| Image 2 Alt Text | Human CACNA2D1 Immunohistochemistry(IHC) 37254 |
| Image 2 URL | Source image |
| Image 3 Description | CACNA2D1 was immunoprecipitated using: Lane A:0.5 mg SHSY-5Y Whole Cell Lysate Lane B:0.5 mg U87-MG Whole Cell Lysate 4 µL anti-CACNA2D1 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein A/G. Primary antibody: Anti-CACNA2D1 rabbit polyclonal antibody,at 1:100 dilution Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 125 kDa Observed band size :125 kDa |
| Image 3 Alt Text | Human CACNA2D1 Immunohistochemistry(IHC) 37253 |
| Image 3 URL | Source image |
| Image 4 Description | CACNA2D1 was immunoprecipitated using: Lane A:0.5 mg SHSY-5Y Whole Cell Lysate Lane B:0.5 mg U87-MG Whole Cell Lysate 4 µL anti-CACNA2D1 rabbit polyclonal antibody and 60 μg of Immunomagnetic beads Protein A/G. Primary antibody: Anti-CACNA2D1 rabbit polyclonal antibody,at 1:100 dilution Secondary antibody: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 125 kDa Observed band size :125 kDa |
| Image 4 Alt Text | Human CACNA2D1 Western blot (WB) 37252 |
| Image 4 URL | Source image |
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Background Information
| Description | Calcium channel, voltage-dependent, alpha-2/delta subunit 1 (CACNA2D1) gene encodes a member of the alpha-2/delta subunit family, proteins are accessory molecules associated with voltage-gated calcium channels and increase the density at the plasma membrane of calcium channels activated by high voltage. CACNA2D1 gene is one of the potential candidate genes influencing carcass and meat quality traits and gene-specific SNPs may be a useful marker for MAS programs in cattle breeding. CACNA2D1 gene is considered to be an important noncytokine candidate gene influencing mastitis. Voltage-gated calcium channel α2δ1 subunit (encoded by the gene CACNA2D1) isoform 5 is a marker of CSCs in hepatocellular carcinoma. CACNA2D1 might be involved in the process of pain by modulating the CGRP and AC-PKA/PKC/MAPK signaling pathways in the dorsal root ganglion. |
| References |
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