| Catalog No. | Size | Price (USD) |
| 13371-T52-50 | 50 µL | $147.96 |
| 13371-T52-100 | 100 µL | $251.64 |
| 13371-T52-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-LRG1 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human LRG1 |
| Immunogen | Recombinant Human LRG1 Protein (Catalog#13371-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human LRG1 (rh LRG1; Catalog#13371-H08H; AAH34389.1; Met1-Gln347). LRG1 specific IgG was purified by Human LRG1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-HMFT1766 Antibody; Anti-LRG Antibody
Image / Experimental Information
| Image 1 Description | Anti-LRG1 rabbit polyclonal antibody at 1:500 dilution Lane A: HepG2 Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: HL60 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:38 kDa Observed band size:38 kDa |
| Image 1 Alt Text | Human LRG1 Western blot (WB) 20265 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-LRG1 rabbit polyclonal antibody at 1:500 dilution Lane A: HepG2 Whole Cell Lysate Lane B: 293T Whole Cell Lysate Lane C: HL60 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:38 kDa Observed band size:38 kDa |
| Image 2 Alt Text | Human LRG1 Immunoprecipitation(IP) 20266 |
| Image 2 URL | Source image |
Background Information
| Full Name | leucine-rich alpha-2-glycoprotein 1 |
| Description | LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. It contains 4 LIM zinc-binding domains and 1 Rho-GAP domain. LRG1 is involved in promoting neovascularization (new blood vessel growth) by causing a switch in transforming growth factor-beta (TGFbeta) signaling in endothelial cells. LRG1 binds to the accessory receptor endoglin and promotes signaling via the ALK1-Smad1/5/8 pathway. It may be a potential therapeutic target for the treatment of diseases where there is aberrant neovascularization. Diseases associated with LRG1 include Appendicitis and Normal Pressure Hydrocephalus. |
| Research Areas |
|
| References |
|
-HD11JN2139-WB.png){kind=link}
