| Catalog No. | Size | Price (USD) |
| 100970-T08-50 | 50 µL | $147.96 |
| 100970-T08-100 | 100 µL | $251.64 |
| 100970-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-MAP1/MOAP1 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human MAP1/MOAP1 |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human MAP1 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human MAP1, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-MAP-1 Antibody; Anti-PNMA4 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human MOAP1 in human brain with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human MAP1 Immunohistochemistry(IHC) 19467 |
| Image 1 URL | Source image |
Background Information
| Full Name | modulator of apoptosis 1 |
| Description | MOAP1 (Modulator Of Apoptosis 1) is a Protein Coding gene. The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. The encoded protein belongs to the PNMA family. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. MOAP1 is widely expressed in the brain, heart, and other tissues. Enforced miR-1228 expression can reduce MOAP1 expression and delay the progression of stress-induced cell apoptosis. The miR-1228 inhibition of cellular apoptosis is significantly attenuated by repressing MOAP1 expression, suggesting the direct interaction between miR-1228 and MOAP1 protein. Among its related pathways are Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins. |
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