Anti-CALM2 Antibody, Rabbit Polyclonal sinobiological 12435-T16

$143.00
In stock
SKU
12435-T16
Catalog No.SizePrice (USD)
12435-T16-5050 µL$147.96
12435-T16-100100 µL$251.64
12435-T16-200200 µL$355.32

General Information

Product nameAnti-CALM2 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CALM2
ImmunogenRecombinant Human CALM2 Protein (Catalog#12435-H07E)
PreparationProduced in rabbits immunized with purified, recombinant Human CALM2 (rh CALM2; Catalog#12435-H07E; P0DP24; Met1-Lys149). CALM2 specific IgG was purified by Human CALM2 affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CALM Antibody; Anti-CALML2 Antibody; Anti-caM Antibody; Anti-CAM1 Antibody; Anti-CAM2 Antibody; Anti-CAM3 Antibody; Anti-CAMB Antibody; Anti-CAMC Antibody; Anti-CAMII Antibody; Anti-CAMIII Antibody; Anti-LQT15 Antibody; Anti-PHKD Antibody; Anti-PHKD2 Antibody

Background Information

Full Namecalmodulin 2 (phosphorylase kinase, delta)
DescriptionCalmodulin 2, also known as CALM2, is a calmodulin. Calmodulin 2 mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). It is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Calmodulin 2 gene may be a genetic determinant of hip osteoarthritis (OA). OA is a degenerative disease characterized by gradual loss of articular cartilage and is a leading cause of disability in elderly populations. CALM2 was most abundantly expressed in articular chondrocytes and OA cartilage.
Related Pathways
  • Actin Dynamics Signaling Pathway
  • B Cell Receptor Signaling Pathway
  • T Cell Receptor Signaling Pathway
References
  1. Egli R, et al. (1993) Localization of the human bona fide calmodulin genes CALM1, CALM2, and CALM3 to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3. Genomics. 16(2): 461-5.
  2. Mikiko, et al. (2002) Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. Mol Biol Cell. 13(9):3235-45.
  3. SenGupta B, et al. (1987) Molecular analysis of human and rat calmodulin complementary DNA clones. Evidence for additional active genes in these species. J Biol Chem. 262(34): 16663-70.

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