Anti-CALML5 Antibody, Rabbit Polyclonal sinobiological 207968-T08
$243.00
In stock
SKU
207968-T08
| Catalog No. | Size | Price (USD) |
| 207968-T08-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-CALML5 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CALML5 |
| Immunogen | E. coli-derived Human CALML5 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CALML5 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CLSP Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CALML5 in human skin with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human CALML5 Immunohistochemistry(IHC) 40376 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CALML5 in human skin with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human CALML5 Immunohistochemistry(IHC) 40377 |
| Image 2 URL | Source image |
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Background Information
| Full Name | calmodulin like 5 |
| Description | Calmodulin-like protein 5, also known as Calmodulin-like skin protein, CALML5 and CLSP, is a protein which contains fourEF-hand domains. CALML5 / CLSP is particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation.The expression is very low in lung. CALML5 / CLSP binds calcium. It may be involved in terminal differentiation of keratinocytes. Coxsackievirus and adenovirus receptor (CAR) is a member of the immunoglobulin (Ig) superfamily and a component of epithelial tight junction. CAR functions as a primary receptor for coxsackievirus B and adenovirus (Ad) infection. CALML5 / CLSP is closely related to CAR. The structure and dynamics of human calmodulin-like skin protein CALML5 / CLSP have been characterized by NMR spectroscopy. The mobility of CALML5 / CLSP has been found to be different for the N-terminal and C-terminal domains. The N-terminal domain is characterized by four stable helices, which experience large fluctuations. This is shown to be due to mutations in the hydrophobic core. The overall N-terminal domain behavior is similar both in the full-length protein and in the isolated domain. |
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