Anti-CAMK2D/CaMKII Delta Antibody, Rabbit Polyclonal sinobiological 203615-T08

$143.00
In stock
SKU
203615-T08
Catalog No.SizePrice (USD)
203615-T08-5050 µL$147.96
203615-T08-100100 µL$251.64
203615-T08-200200 µL$355.32

General Information

Product nameAnti-CAMK2D/CaMKII Delta Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human, Cynomolgus
SpecificityHuman, Cynomolgus
ImmunogenE. coli-derived Human Camk2d fragment
PreparationProduced in rabbits immunized with E. coli-derived Human Camk2d fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CAMK2D Antibody; Anti-CAMKD Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human CAMK2D in cynomolgus heart with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman Camk2d Immunohistochemistry(IHC) 22547
Image 1 URLSource image

Background Information

DescriptionThe product of CAMK2D gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns. CAMK2D (Calcium/Calmodulin Dependent Protein Kinase II Delta) is located on human chromosome 4q26. 180 organisms have orthologs with human gene CAMK2D.
References
  1. Xu X, et al. (2018) Overexpression of smarca2 or camk2d is associated with cisplatin resistance in human epithelial ovarian cancer. Oncol Lett 16 (3): 3796-3804.

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