Anti-MTG1 Antibody, Rabbit Polyclonal sinobiological 203285-T32
$243.00
In stock
SKU
203285-T32
| Catalog No. | Size | Price (USD) |
| 203285-T32-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-MTG1 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human MTG1 |
| Immunogen | E. coli-derived Human MTG1 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human MTG1 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-GTP Antibody; Anti-GTPBP7 Antibody
Image / Experimental Information
| Image 1 Description | Anti-MTG1 rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:37 kDa Observed band size:37 kDa |
| Image 1 Alt Text | Human MTG1 Western blot (WB) 47501 |
| Image 1 URL | Source image |
Background Information
| Full Name | mitochondrial ribosome-associated GTPase 1 |
| Description | Mitochondrial GTPases 1 (MTG1) regulates mitochondrial ribosome assembly and translation. MTG1 protects against pressure overload-induced cardiac hypertrophy and dysfunction by preserving mitochondrial function and reducing oxidative stress and downstream TAK1 stress signaling. MTG1-silencing in human cardiomyocytes and developing zebrafish revealed early cardiovascular lesions. The MTG1 gene of Saccharomyces cerevisiae, corresponding to ORF YMR097c on chromosome XIII, codes for a mitochondrial protein essential for respiratory competence. A human homolog of Mtg1p capable of partially rescuing the respiratory deficiency of a yeast mtg1 mutant has also been localized in mitochondria. The respiratory deficiency of mtg1 mutants stems from a defect in mitochondrial protein synthesis. |
| References |
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