| Catalog No. | Size | Price (USD) |
| 201320-T40-50 | 50 µL | $147.96 |
| 201320-T40-100 | 100 µL | $251.64 |
| 201320-T40-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CAMLG Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CAMLG |
| Immunogen | E. coli-derived Human CAMLG fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CAMLG fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CAML Antibody; Anti-CDG2Z Antibody; Anti-GET2 Antibody
Image / Experimental Information
| Image 1 Description | Anti-CAMLG rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: U-87 MG Whole Cell Lysate Lane C: SH-SY5Y Whole Cell Lysate Lane D: U-251MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:33 kDa Observed band size:34 kDa |
| Image 1 Alt Text | Human CAMLG Western blot (WB) 28744 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-CAMLG rabbit polyclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: U-87 MG Whole Cell Lysate Lane C: SH-SY5Y Whole Cell Lysate Lane D: U-251MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:33 kDa Observed band size:34 kDa |
| Image 2 Alt Text | Human CAMLG Immunohistochemistry(IHC) 28745 |
| Image 2 URL | Source image |
Background Information
| Full Name | calcium modulating ligand |
| Description | The CAMLG gene encodes a novel cyclophilin B-binding protein called calcium-modulating cyclophilin ligand, which appears to be involved in the regulation of calcium signaling in T lymphocytes and other cells. CAMLG is the major host cell PilA binding protein. The murine homolog, Caml, was localized by interspecific backcross analysis to the middle of chromosome 13. By fluorescence in situ hybridization, this gene was localized to human chromosome 5 in a region (q23) known to be syntenic to mouse chromosome 13. Expression of human CAML (encoded by CAMLG) in AGM cells conferred a strong restriction of virus release that was reversed by Vpu and HIV-2 Env, suggesting that CAML is the mechanistic link between these two viral regulators. Depletion of CAML in human cells eliminated the need for Vpu in enhancing HIV-1 and murine leukemia virus release. |
| References |
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