| Catalog No. | Size | Price (USD) |
| 11066-R010-200 | 200 µg | $296.22 |
| 11066-R010-500 | 500 µg | $444.33 |
General Information
| Product name | VEGF165 Neutralizing Antibody |
| Validated applications | ELISA(Cap) (FAQ Protocol), Neutralization |
| Species reactivity | Reacts with: Human, Cynomolgus |
| Specificity | Human, Cynomolgus VEGF165/VEGFA Has cross-reactivity in ELISA with Mouse VEGF164 (Catalog # 50159-MNAB) Rat VEGF164 (Catalog # 80006-RNAB) |
| Immunogen | Recombinant Human / Cynomolgus VEGF165/VEGFA protein (Catalog#11066-HNAB) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human / Cynomolgus VEGF165/VEGFA (rh VEGF165/VEGFA; Catalog#11066-HNAB; P15692-4; Met1-Arg191) and was produced using recombinant antibody technology. |
| Source | Monoclonal Rabbit IgG Clone #R010 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Endotoxin | Please contact us for more information. |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Image / Experimental Information
| Image 1 Description | Measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 10-47 ng/mL in the presence of 10 ng/mL human VEGF165. |
| Image 1 Alt Text | Human VEGF/VEGFA/VEGF165 Blocking/Neutralization (B/N) 5592 |
| Image 1 URL | Source image |
Background Information
| Full Name | vascular endothelial growth factor A |
| Description | Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor. |
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| References |
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title: FGFR2 is a Crucial Factor for Adipose‐Derived Mesenchymal Stem Cells in Promoting Diabetic Foot Ulcer Healing Through Angiogenesis
authors: Jing Cao; Zichao Liu; ...; Yuemei Yang
journal: Journal of Cellular and Molecular Medicine
date: 2025-11-13
pmid: 41230809
doi: 10.1111/jcmm.70942
cited_by_count: 0
techniques: Cell Culture; Enzyme-linked Immunosorbent Assay; Migration; Tube Formation Assay
bioz_score: 93
title: LncRNA TUG1 Repressed Angiogenesis by Promoting the Ubiquitination of HuR and Inhibiting Its Nuclear Translocation in Cerebral Ischemic Reperfusion Injury
authors: Hongxiang Jiang; Qiang Cai; ...; Qianxue Chen
journal: Advanced Science
date: 2025-01-31
pmid: 39887590
pmcid: 11948051
cited_by_count: 4
techniques: Binding Assay; Comparison; Construct; Control; Enzyme-linked Immunosorbent Assay; Expressing; Fluorescence; Immunohistochemical staining; In Vitro; In Vivo; MANN-WHITNEY; Migration; Modification; Over Expression; Plasmid Preparation; Quantitative RT-PCR; Staining; Translocation Assay; Ubiquitin Proteomics; Western Blot
bioz_score: 93
title: THBS1 promotes angiogenesis and accelerates ESCC malignant progression by the HIF-1/VEGF signaling pathway.
authors: Xiao Zhou; Qiaoxi Xia; ...; Zepeng Du
journal: Cell biology international
date: 2024-02-14
pmid: 38233982
doi: 10.1002/cbin.12126
cited_by_count: 6
techniques: Binding Assay; Blocking Assay; Concentration Assay; Enzyme-linked Immunosorbent Assay; Incubation
bioz_score: 93
title: Kaposi’s sarcoma-associated herpesvirus promotes mesenchymal-to-endothelial transition by resolving the bivalent chromatin of PROX1 gene
authors: Yao Ding; Weikang Chen; ...; Pinghui Feng
journal: PLoS Pathogens
date: 2021-09-07
pmid: 34492084
doi: 10.1371/journal.ppat.1009847
pmcid: 8448337
cited_by_count: 12
techniques: Chemotaxis Assay; Expressing; Incubation; Infection; Invasion Assay; Marker; Negative Control; Plasmid Preparation; Quantitative RT-PCR; Software; Staining; Transduction; Transfection; Tube Formation Assay; Western Blot
bioz_score: 93
title: Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis
authors: Yi Shi; Ze Liu; ...; Tanya Paull
journal: PLoS Biology
date: 2020-12-22
pmid: 33351793
doi: 10.1371/journal.pbio.3000991
pmcid: 7755189
cited_by_count: 21
techniques: Activation Assay; Angiogenesis Assay; Binding Assay; Cell Culture; Chromatin Immunoprecipitation; Concentration Assay; Control; Electrophoresis; Endothelial Cell Tube Formation Assay; Enzyme-linked Immunosorbent Assay; Expressing; FLAG-tag; Immunofluorescence; Immunoprecipitation; In Vitro; Injection; Labeling; Membrane; Microscopy; Mobility Shift; Mutagenesis; Plasmid Preparation; Purification; Quantitative RT-PCR; Real-time Polymerase Chain Reaction; Recombinant; Reverse Transcription; Sequencing; Small Interfering RNA; Software; Stable Transfection; Staining; Transfection; Tube Formation Assay; Western Blot; shRNA
bioz_score: 93
title: Internalization of HMGB1 (High Mobility Group Box 1) Promotes Angiogenesis in Endothelial Cells
authors: Jiaoli Lan; Haihua Luo; ...; Jia Xu
journal: Arteriosclerosis, thrombosis, and vascular biology
date: 2020-12-01
doi: 10.1161/atvbaha.120.315151
cited_by_count: 21
techniques: Incubation; Neutralizing Assay; Proliferation Assay; Transwell Migration Assay; Wound Healing Assay
bioz_score: 93
title: Inhibitory effect and molecular mechanism of mesenchymal stem cells on NSCLC cells.
authors: Mengwu Pan; Lingling Hou; ...; Lishu Zhang
journal: Molecular and cellular biochemistry
date: 2018-07-10
pmid: 28887716
doi: 10.1007/s11010-017-3174-y
cited_by_count: 9
techniques: Cell Culture; In Vitro; MTT Assay; Recombinant
bioz_score: 93
