| Catalog No. | Size | Price (USD) |
| 10338-T24-50 | 50 µL | $147.96 |
| 10338-T24-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-IFNGR1 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human IFNGR1 |
| Immunogen | Recombinant Human IFNGR1 Protein (Catalog#10338-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human IFNGR1 (rh IFNGR1; Catalog#10338-H08H; NP_000407.1; Met1-Gly245). IFNGR1 specific IgG was purified by Human IFNGR1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD119 Antibody; Anti-IFNGR Antibody; Anti-IMD27A Antibody; Anti-IMD27B Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human IFNGR1 in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human IFNGR1 Immunohistochemistry(IHC) 35588 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human IFNGR1 in human placenta with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human IFNGR1 Immunohistochemistry(IHC) 35589 |
| Image 2 URL | Source image |
Background Information
| Full Name | interferon gamma receptor 1 |
| Description | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon-gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interferon receptor while the IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types. |
| References |
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