Recombinant Anti-IL-33 Antibody, Rabbit Monoclonal sinobiological 10368-R742

$243.00
In stock
SKU
10368-R742
Catalog No.SizePrice (USD)
10368-R742-100100 µL$251.64

General Information

Product nameRecombinant Anti-IL-33 Antibody, Rabbit Monoclonal
Validated applicationsELISA (FAQ Protocol), IHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman IL-33
ImmunogenRecombinant Human IL-33 Protein (Catalog#10368-HNAE)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Human IL-33 (rh IL-33; Catalog#10368-HNAE; NP_254274.1; Ser112-Thr270).
SourceMonoclonal Rabbit IgG Clone #742
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-C9orf26 Antibody; Anti-DKFZp586H0523 Antibody; Anti-DVS27 Antibody; Anti-IL1F11 Antibody; Anti-NF-HEV Antibody; Anti-NFEHEV Antibody; Anti-NFHEV Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human IL-33 in human stomach with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman IL-33 Immunohistochemistry(IHC) 37303
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining of human IL-33 in human stomach with rabbit monoclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.
Image 2 Alt TextHuman IL-33 Immunohistochemistry(IHC) 37302
Image 2 URLSource image

Background Information

Full Nameinterleukin 33
DescriptionInterleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyer's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.
Related Pathways
  • IL1 signaling pathway
References
  1. Iikura M, et al. (2007) IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest. 87(10): 971-8.
  2. Lamkanfi M, et al. (2009) IL-33 raises alarm. Immunity. 31(1): 5-7.

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