| Catalog No. | Size | Price (USD) |
| 310196-T08-50 | 50 µL | $147.96 |
| 310196-T08-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-CASP8/ALPS2B Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CASP8/ALPS2B |
| Immunogen | E. coli-derived Human CASP8/ALPS2B fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human CASP8/ALPS2B fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-ALPS2B Antibody; Anti-CAP4 Antibody; Anti-Casp-8 Antibody; Anti-FLICE Antibody; Anti-MACH Antibody; Anti-MCH5 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CASP8 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human CASP8/ALPS2B Immunohistochemistry(IHC) 35648 |
| Image 1 URL | Source image |
Background Information
| Full Name | caspase 8, apoptosis-related cysteine peptidase |
| Description | Caspase 8 is a cysteine dependent endoprotease that plays a key role in the regulation of apoptosis (also referred as programmed cell death), an event which is known to be essential in growth and development of embryo, and maintenance of tissue homeostasis. Caspases are broadly classified as apoptosis or inflammation regulatory caspases based on their role in respective processes. Of those known, caspase - 3, -6, -7, -8 and -9 are categorized as apoptotic caspases, whereas caspase -1, -4, -5 and -12 are grouped as inflammatory caspases. The apoptotic caspases are further classified into initiator caspases (caspase -8 and -9) and effecter caspases (caspase -3, -6 and -7) based on their role in transducing the apoptotic signals emanating at the cell membrane. |
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