| Catalog No. | Size | Price (USD) |
| 205118-T08-50 | 50 µL | $147.96 |
| 205118-T08-100 | 100 µL | $251.64 |
| 205118-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-INSL5 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human INSL5 |
| Immunogen | E. coli-derived Human INSL5 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human INSL5 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-PRO182 Antibody; Anti-UNQ156 Antibody; Anti-UNQ156/PRO182 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human INSL5 in human rectum with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human INSL5 Immunohistochemistry(IHC) 25385 |
| Image 1 URL | Source image |
Background Information
| Description | Insulin-like peptide-5 (INSL5) is an orexigenic gut hormone found in a subset of colonic and rectal enteroendocrine L-cells together with the anorexigenic hormones glucagon-like peptide-1 (GLP-1) and peptideYY (PYY). Unlike GLP-1 and PYY, INSL5 levels are elevated by calorie restriction. INSL5 is a member of the insulin/relaxin gene family sharing a common structural signature comprised of an A and B chain with a conserved cysteine bridging pattern. INSL5 is expressed at highest levels in the colon of both mice and humans, with lower expression found for example in thymus and testis and within the colon it is expressed in enteroendocrine L-cells, which also secrete glucagon-like peptide-1 (GLP-1) and peptideYY (PYY). |
| References |
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